Immunology Quiz: Test Your Knowledge Immunology QuizChallenge your understanding of immunology with our carefully curated quiz covering foundational to advanced concepts. This interactive set of multiple-choice questions (MCQs) includes topics like innate and adaptive immunity, antibodies, antigen presentation, hypersensitivity reactions, and immune disorders. Perfect for students, competitive exam aspirants, and microbiology enthusiasts looking to revise or reinforce their knowledge. Start learning smarter with instant feedback and explanations on LearnMicrobiology.com! NameEmail 1 / 30Which organ is responsible for the maturation of T lymphocytes? Liver Thymus Bone marrow Spleen 2 / 30Which transcription factor is activated by NF-κB in immune signaling? MyD88 NF-κB itself STAT6 p53 3 / 30The complement system enhances immunity by: Increasing T cell count Opsonization and cell lysis Cell apoptosis Antigen production 4 / 30The process of central tolerance occurs in the: Bloodstream Thymus and bone marrow Peripheral lymph nodes Liver 5 / 30Which antibody is most abundant in human serum? IgM IgE IgA IgG 6 / 30Which of the following diseases is an example of autoimmunity? Asthma HIV/AIDS Rheumatoid arthritis Tuberculosis 7 / 30Phagocytosis is carried out primarily by: Mast cells Macrophages T-helper cells B cells 8 / 30MHC class I molecules present antigens to: CD8+ T cells B cells CD4+ T cells Macrophages 9 / 30Which pathway of complement activation requires antibodies? Lectin Alternative Classical Lytic 10 / 30Which interleukin is known as the "T cell growth factor"? IL-10 IL-1 IL-2 IL-6 11 / 30Which of the following best describes antigenic drift? Inactivation of antigen Minor mutations over time Sudden, major changes in antigen Immune memory loss 12 / 30The term "opsonization" refers to: Coating of pathogens to enhance phagocytosis Lymphocyte apoptosis Antibody switching Antigen destruction by acid 13 / 30Histamine release is most closely associated with which immune response? Antibody production Allergy Autoimmunity Inflammation 14 / 30Toll-like receptors (TLRs) are part of which immune system?Adaptive Innate Humoral Adaptive Passive 15 / 30Which molecule is crucial for T-cell activation along with the TCR–MHC interaction? CD40 CD28 IgE CD19 16 / 30Which type of hypersensitivity is antibody-mediated cytotoxic? Type II Type I Type III Type IV 17 / 30Which immunoglobulin appears first during a primary immune response? IgM IgA IgG IgE 18 / 30Which of the following is NOT an antigen-presenting cell? Erythrocyte B cell Macrophage Dendritic cell 19 / 30Which of the following immunoglobulins can cross the placenta? IgM IgE IgA IgG 20 / 30Which is a function of Regulatory T cells (Tregs)? Suppress immune response Stimulate inflammation Present antigens Kill infected cells 21 / 30What is the primary function of the immune system? Defense against pathogens Oxygen transport Digestion Hormone production 22 / 30Which of these cells produces antibodies? T cells Dendritic cells Macrophages Plasma cells 23 / 30Which cell surface marker is found on all helper T cells? CD56 CD4 CD19 CD8 24 / 30What is the function of the J chain in immunoglobulins? Inhibits antibody function Breaks down antigens Enhances Fc receptor binding Joins monomers of IgA and IgM 25 / 30Clonal selection refers to: Removal of self-reactive lymphocytes Expansion of specific lymphocytes after antigen recognition Natural killer cell activation Generation of T cell receptors 26 / 30Which is a feature of a secondary immune response? Faster and stronger antibody production Low antibody titers Slow onset IgM predominance 27 / 30Which cytokine is primarily responsible for fever? IL-4 IL-10 IL-1 IFN-gamma 28 / 30What type of immunity is acquired through vaccination? Natural immunity Passive immunity Artificial active immunity Innate immunity 29 / 30Which of the following is a component of the innate immune system? Natural killer (NK) cells Memory B cells T cells Antibodies 30 / 30Which immunoglobulin is primarily involved in mucosal immunity? IgM IgG IgE IgA Your score isThe average score is 65% 0% Restart quiz
