Immunology Quiz: Test Your Knowledge Immunology QuizChallenge your understanding of immunology with our carefully curated quiz covering foundational to advanced concepts. This interactive set of multiple-choice questions (MCQs) includes topics like innate and adaptive immunity, antibodies, antigen presentation, hypersensitivity reactions, and immune disorders. Perfect for students, competitive exam aspirants, and microbiology enthusiasts looking to revise or reinforce their knowledge. Start learning smarter with instant feedback and explanations on LearnMicrobiology.com! NameEmail 1 / 30Toll-like receptors (TLRs) are part of which immune system?Adaptive Humoral Adaptive Innate Passive 2 / 30What is the primary function of the immune system? Hormone production Oxygen transport Defense against pathogens Digestion 3 / 30Histamine release is most closely associated with which immune response? Inflammation Antibody production Allergy Autoimmunity 4 / 30Which of these cells produces antibodies? Dendritic cells T cells Plasma cells Macrophages 5 / 30The process of central tolerance occurs in the: Bloodstream Peripheral lymph nodes Liver Thymus and bone marrow 6 / 30Which is a function of Regulatory T cells (Tregs)? Stimulate inflammation Kill infected cells Suppress immune response Present antigens 7 / 30Which of the following immunoglobulins can cross the placenta? IgM IgG IgA IgE 8 / 30MHC class I molecules present antigens to: CD4+ T cells CD8+ T cells Macrophages B cells 9 / 30What is the function of the J chain in immunoglobulins? Breaks down antigens Enhances Fc receptor binding Inhibits antibody function Joins monomers of IgA and IgM 10 / 30Clonal selection refers to: Expansion of specific lymphocytes after antigen recognition Removal of self-reactive lymphocytes Generation of T cell receptors Natural killer cell activation 11 / 30Which cytokine is primarily responsible for fever? IL-1 IL-10 IL-4 IFN-gamma 12 / 30Which immunoglobulin is primarily involved in mucosal immunity? IgE IgM IgG IgA 13 / 30The term "opsonization" refers to: Antigen destruction by acid Coating of pathogens to enhance phagocytosis Lymphocyte apoptosis Antibody switching 14 / 30Which cell surface marker is found on all helper T cells? CD19 CD56 CD4 CD8 15 / 30Which antibody is most abundant in human serum? IgE IgM IgA IgG 16 / 30The complement system enhances immunity by: Antigen production Opsonization and cell lysis Cell apoptosis Increasing T cell count 17 / 30Phagocytosis is carried out primarily by: Macrophages B cells Mast cells T-helper cells 18 / 30Which interleukin is known as the "T cell growth factor"? IL-1 IL-2 IL-10 IL-6 19 / 30Which is a feature of a secondary immune response? Slow onset Low antibody titers Faster and stronger antibody production IgM predominance 20 / 30Which pathway of complement activation requires antibodies? Alternative Lytic Classical Lectin 21 / 30Which immunoglobulin appears first during a primary immune response? IgM IgA IgE IgG 22 / 30What type of immunity is acquired through vaccination? Passive immunity Innate immunity Natural immunity Artificial active immunity 23 / 30Which of the following diseases is an example of autoimmunity? HIV/AIDS Tuberculosis Asthma Rheumatoid arthritis 24 / 30Which type of hypersensitivity is antibody-mediated cytotoxic? Type II Type III Type IV Type I 25 / 30Which of the following is a component of the innate immune system? T cells Natural killer (NK) cells Memory B cells Antibodies 26 / 30Which of the following is NOT an antigen-presenting cell? Macrophage B cell Erythrocyte Dendritic cell 27 / 30Which organ is responsible for the maturation of T lymphocytes? Thymus Spleen Liver Bone marrow 28 / 30Which of the following best describes antigenic drift? Sudden, major changes in antigen Inactivation of antigen Immune memory loss Minor mutations over time 29 / 30Which transcription factor is activated by NF-κB in immune signaling? p53 STAT6 NF-κB itself MyD88 30 / 30Which molecule is crucial for T-cell activation along with the TCR–MHC interaction? CD40 IgE CD28 CD19 Your score isThe average score is 64% 0% Restart quiz