Immunology Quiz: Test Your Knowledge Immunology QuizChallenge your understanding of immunology with our carefully curated quiz covering foundational to advanced concepts. This interactive set of multiple-choice questions (MCQs) includes topics like innate and adaptive immunity, antibodies, antigen presentation, hypersensitivity reactions, and immune disorders. Perfect for students, competitive exam aspirants, and microbiology enthusiasts looking to revise or reinforce their knowledge. Start learning smarter with instant feedback and explanations on LearnMicrobiology.com! NameEmail 1 / 30Which molecule is crucial for T-cell activation along with the TCR–MHC interaction? IgE CD28 CD40 CD19 2 / 30Which immunoglobulin appears first during a primary immune response? IgM IgA IgG IgE 3 / 30Which cell surface marker is found on all helper T cells? CD19 CD56 CD4 CD8 4 / 30Which pathway of complement activation requires antibodies? Lytic Classical Alternative Lectin 5 / 30Which of the following diseases is an example of autoimmunity? Rheumatoid arthritis HIV/AIDS Asthma Tuberculosis 6 / 30Which antibody is most abundant in human serum? IgG IgE IgA IgM 7 / 30What is the function of the J chain in immunoglobulins? Joins monomers of IgA and IgM Enhances Fc receptor binding Inhibits antibody function Breaks down antigens 8 / 30The process of central tolerance occurs in the: Liver Bloodstream Thymus and bone marrow Peripheral lymph nodes 9 / 30Which is a function of Regulatory T cells (Tregs)? Suppress immune response Stimulate inflammation Present antigens Kill infected cells 10 / 30What is the primary function of the immune system? Hormone production Defense against pathogens Digestion Oxygen transport 11 / 30The term "opsonization" refers to: Antibody switching Coating of pathogens to enhance phagocytosis Lymphocyte apoptosis Antigen destruction by acid 12 / 30MHC class I molecules present antigens to: CD4+ T cells Macrophages CD8+ T cells B cells 13 / 30What type of immunity is acquired through vaccination? Natural immunity Artificial active immunity Innate immunity Passive immunity 14 / 30The complement system enhances immunity by: Antigen production Opsonization and cell lysis Cell apoptosis Increasing T cell count 15 / 30Histamine release is most closely associated with which immune response? Antibody production Autoimmunity Inflammation Allergy 16 / 30Which of these cells produces antibodies? Dendritic cells T cells Macrophages Plasma cells 17 / 30Which of the following is NOT an antigen-presenting cell? Erythrocyte Dendritic cell Macrophage B cell 18 / 30Which cytokine is primarily responsible for fever? IFN-gamma IL-4 IL-10 IL-1 19 / 30Which type of hypersensitivity is antibody-mediated cytotoxic? Type III Type IV Type I Type II 20 / 30Toll-like receptors (TLRs) are part of which immune system?Adaptive Humoral Passive Innate Adaptive 21 / 30Which immunoglobulin is primarily involved in mucosal immunity? IgE IgA IgM IgG 22 / 30Which organ is responsible for the maturation of T lymphocytes? Liver Thymus Spleen Bone marrow 23 / 30Phagocytosis is carried out primarily by: Macrophages B cells T-helper cells Mast cells 24 / 30Which interleukin is known as the "T cell growth factor"? IL-6 IL-2 IL-10 IL-1 25 / 30Which of the following best describes antigenic drift? Immune memory loss Inactivation of antigen Sudden, major changes in antigen Minor mutations over time 26 / 30Which of the following is a component of the innate immune system? T cells Memory B cells Antibodies Natural killer (NK) cells 27 / 30Which transcription factor is activated by NF-κB in immune signaling? p53 STAT6 MyD88 NF-κB itself 28 / 30Which of the following immunoglobulins can cross the placenta? IgE IgM IgA IgG 29 / 30Clonal selection refers to: Generation of T cell receptors Removal of self-reactive lymphocytes Expansion of specific lymphocytes after antigen recognition Natural killer cell activation 30 / 30Which is a feature of a secondary immune response? Slow onset IgM predominance Low antibody titers Faster and stronger antibody production Your score isThe average score is 64% 0% Restart quiz
