Immunology Quiz: Test Your Knowledge Immunology QuizChallenge your understanding of immunology with our carefully curated quiz covering foundational to advanced concepts. This interactive set of multiple-choice questions (MCQs) includes topics like innate and adaptive immunity, antibodies, antigen presentation, hypersensitivity reactions, and immune disorders. Perfect for students, competitive exam aspirants, and microbiology enthusiasts looking to revise or reinforce their knowledge. Start learning smarter with instant feedback and explanations on LearnMicrobiology.com! NameEmail 1 / 30Which is a feature of a secondary immune response? Faster and stronger antibody production IgM predominance Low antibody titers Slow onset 2 / 30Which immunoglobulin is primarily involved in mucosal immunity? IgE IgA IgM IgG 3 / 30What is the function of the J chain in immunoglobulins? Breaks down antigens Joins monomers of IgA and IgM Enhances Fc receptor binding Inhibits antibody function 4 / 30Which of the following best describes antigenic drift? Sudden, major changes in antigen Inactivation of antigen Immune memory loss Minor mutations over time 5 / 30The term "opsonization" refers to: Antibody switching Lymphocyte apoptosis Coating of pathogens to enhance phagocytosis Antigen destruction by acid 6 / 30Histamine release is most closely associated with which immune response? Antibody production Inflammation Allergy Autoimmunity 7 / 30Which antibody is most abundant in human serum? IgM IgE IgA IgG 8 / 30What type of immunity is acquired through vaccination? Innate immunity Passive immunity Natural immunity Artificial active immunity 9 / 30Which immunoglobulin appears first during a primary immune response? IgG IgE IgA IgM 10 / 30What is the primary function of the immune system? Digestion Hormone production Defense against pathogens Oxygen transport 11 / 30Which transcription factor is activated by NF-κB in immune signaling? p53 NF-κB itself MyD88 STAT6 12 / 30Which of the following diseases is an example of autoimmunity? Rheumatoid arthritis Tuberculosis Asthma HIV/AIDS 13 / 30Which of the following is a component of the innate immune system? T cells Natural killer (NK) cells Memory B cells Antibodies 14 / 30Which molecule is crucial for T-cell activation along with the TCR–MHC interaction? IgE CD28 CD19 CD40 15 / 30Which of the following is NOT an antigen-presenting cell? Dendritic cell B cell Macrophage Erythrocyte 16 / 30Which of the following immunoglobulins can cross the placenta? IgA IgE IgG IgM 17 / 30Which cytokine is primarily responsible for fever? IL-10 IFN-gamma IL-1 IL-4 18 / 30Which organ is responsible for the maturation of T lymphocytes? Spleen Thymus Bone marrow Liver 19 / 30Clonal selection refers to: Expansion of specific lymphocytes after antigen recognition Natural killer cell activation Removal of self-reactive lymphocytes Generation of T cell receptors 20 / 30Which type of hypersensitivity is antibody-mediated cytotoxic? Type III Type IV Type I Type II 21 / 30Phagocytosis is carried out primarily by: Mast cells B cells Macrophages T-helper cells 22 / 30Which of these cells produces antibodies? Dendritic cells T cells Plasma cells Macrophages 23 / 30The process of central tolerance occurs in the: Liver Thymus and bone marrow Peripheral lymph nodes Bloodstream 24 / 30Which cell surface marker is found on all helper T cells? CD8 CD4 CD56 CD19 25 / 30Which is a function of Regulatory T cells (Tregs)? Stimulate inflammation Kill infected cells Suppress immune response Present antigens 26 / 30Which interleukin is known as the "T cell growth factor"? IL-1 IL-2 IL-10 IL-6 27 / 30Toll-like receptors (TLRs) are part of which immune system?Adaptive Adaptive Humoral Passive Innate 28 / 30Which pathway of complement activation requires antibodies? Alternative Lytic Lectin Classical 29 / 30The complement system enhances immunity by: Opsonization and cell lysis Cell apoptosis Antigen production Increasing T cell count 30 / 30MHC class I molecules present antigens to: CD8+ T cells CD4+ T cells B cells Macrophages Your score isThe average score is 52% 0% Restart quiz