Immunology Quiz: Test Your Knowledge Immunology QuizChallenge your understanding of immunology with our carefully curated quiz covering foundational to advanced concepts. This interactive set of multiple-choice questions (MCQs) includes topics like innate and adaptive immunity, antibodies, antigen presentation, hypersensitivity reactions, and immune disorders. Perfect for students, competitive exam aspirants, and microbiology enthusiasts looking to revise or reinforce their knowledge. Start learning smarter with instant feedback and explanations on LearnMicrobiology.com! NameEmail 1 / 30Which molecule is crucial for T-cell activation along with the TCR–MHC interaction? IgE CD28 CD40 CD19 2 / 30Which pathway of complement activation requires antibodies? Lectin Lytic Alternative Classical 3 / 30Phagocytosis is carried out primarily by: Macrophages B cells Mast cells T-helper cells 4 / 30Which of the following immunoglobulins can cross the placenta? IgE IgG IgM IgA 5 / 30What is the function of the J chain in immunoglobulins? Joins monomers of IgA and IgM Inhibits antibody function Breaks down antigens Enhances Fc receptor binding 6 / 30Which of the following diseases is an example of autoimmunity? Rheumatoid arthritis Asthma Tuberculosis HIV/AIDS 7 / 30Toll-like receptors (TLRs) are part of which immune system?Adaptive Passive Innate Adaptive Humoral 8 / 30Which of these cells produces antibodies? Macrophages Dendritic cells Plasma cells T cells 9 / 30Which is a feature of a secondary immune response? Slow onset Low antibody titers Faster and stronger antibody production IgM predominance 10 / 30Which is a function of Regulatory T cells (Tregs)? Stimulate inflammation Kill infected cells Suppress immune response Present antigens 11 / 30Which immunoglobulin appears first during a primary immune response? IgG IgA IgE IgM 12 / 30Which antibody is most abundant in human serum? IgM IgG IgE IgA 13 / 30The process of central tolerance occurs in the: Liver Peripheral lymph nodes Bloodstream Thymus and bone marrow 14 / 30Which cell surface marker is found on all helper T cells? CD4 CD56 CD19 CD8 15 / 30Which of the following is NOT an antigen-presenting cell? B cell Dendritic cell Erythrocyte Macrophage 16 / 30Which of the following is a component of the innate immune system? Memory B cells Antibodies T cells Natural killer (NK) cells 17 / 30The complement system enhances immunity by: Antigen production Increasing T cell count Cell apoptosis Opsonization and cell lysis 18 / 30Which transcription factor is activated by NF-κB in immune signaling? p53 NF-κB itself MyD88 STAT6 19 / 30What is the primary function of the immune system? Hormone production Defense against pathogens Digestion Oxygen transport 20 / 30Which interleukin is known as the "T cell growth factor"? IL-6 IL-10 IL-1 IL-2 21 / 30Histamine release is most closely associated with which immune response? Antibody production Allergy Inflammation Autoimmunity 22 / 30The term "opsonization" refers to: Coating of pathogens to enhance phagocytosis Antibody switching Lymphocyte apoptosis Antigen destruction by acid 23 / 30MHC class I molecules present antigens to: Macrophages CD8+ T cells CD4+ T cells B cells 24 / 30Which organ is responsible for the maturation of T lymphocytes? Thymus Liver Bone marrow Spleen 25 / 30Which immunoglobulin is primarily involved in mucosal immunity? IgA IgM IgE IgG 26 / 30Which cytokine is primarily responsible for fever? IL-4 IL-1 IFN-gamma IL-10 27 / 30Clonal selection refers to: Expansion of specific lymphocytes after antigen recognition Removal of self-reactive lymphocytes Natural killer cell activation Generation of T cell receptors 28 / 30Which type of hypersensitivity is antibody-mediated cytotoxic? Type IV Type I Type III Type II 29 / 30Which of the following best describes antigenic drift? Minor mutations over time Sudden, major changes in antigen Inactivation of antigen Immune memory loss 30 / 30What type of immunity is acquired through vaccination? Passive immunity Innate immunity Artificial active immunity Natural immunity Your score isThe average score is 52% 0% Restart quiz