Immunology QuizChallenge your understanding of immunology with our carefully curated quiz covering foundational to advanced concepts. This interactive set of multiple-choice questions (MCQs) includes topics like innate and adaptive immunity, antibodies, antigen presentation, hypersensitivity reactions, and immune disorders. Perfect for students, competitive exam aspirants, and microbiology enthusiasts looking to revise or reinforce their knowledge. Start learning smarter with instant feedback and explanations on LearnMicrobiology.com! NameEmail 1 / 30Which cytokine is primarily responsible for fever? IL-1 IL-4 IFN-gamma IL-10 2 / 30What type of immunity is acquired through vaccination? Natural immunity Innate immunity Passive immunity Artificial active immunity 3 / 30Which of the following is NOT an antigen-presenting cell? B cell Macrophage Erythrocyte Dendritic cell 4 / 30Which cell surface marker is found on all helper T cells? CD19 CD56 CD8 CD4 5 / 30The term "opsonization" refers to: Antibody switching Antigen destruction by acid Lymphocyte apoptosis Coating of pathogens to enhance phagocytosis 6 / 30Which organ is responsible for the maturation of T lymphocytes? Spleen Liver Thymus Bone marrow 7 / 30Which transcription factor is activated by NF-κB in immune signaling? p53 STAT6 NF-κB itself MyD88 8 / 30Which pathway of complement activation requires antibodies? Lectin Alternative Classical Lytic 9 / 30MHC class I molecules present antigens to: CD4+ T cells CD8+ T cells B cells Macrophages 10 / 30Which of the following diseases is an example of autoimmunity? Tuberculosis Rheumatoid arthritis HIV/AIDS Asthma 11 / 30Which of the following immunoglobulins can cross the placenta? IgM IgA IgG IgE 12 / 30Which of the following is a component of the innate immune system? Antibodies Memory B cells Natural killer (NK) cells T cells 13 / 30Which is a feature of a secondary immune response? Slow onset Faster and stronger antibody production IgM predominance Low antibody titers 14 / 30Which antibody is most abundant in human serum? IgM IgA IgE IgG 15 / 30Which immunoglobulin appears first during a primary immune response? IgM IgA IgG IgE 16 / 30Which of these cells produces antibodies? Dendritic cells Plasma cells T cells Macrophages 17 / 30Histamine release is most closely associated with which immune response? Antibody production Autoimmunity Allergy Inflammation 18 / 30Which type of hypersensitivity is antibody-mediated cytotoxic? Type II Type III Type I Type IV 19 / 30Which of the following best describes antigenic drift? Immune memory loss Sudden, major changes in antigen Minor mutations over time Inactivation of antigen 20 / 30What is the primary function of the immune system? Oxygen transport Defense against pathogens Digestion Hormone production 21 / 30Phagocytosis is carried out primarily by: T-helper cells Mast cells B cells Macrophages 22 / 30Clonal selection refers to: Natural killer cell activation Generation of T cell receptors Expansion of specific lymphocytes after antigen recognition Removal of self-reactive lymphocytes 23 / 30Which is a function of Regulatory T cells (Tregs)? Stimulate inflammation Kill infected cells Suppress immune response Present antigens 24 / 30The process of central tolerance occurs in the: Thymus and bone marrow Liver Bloodstream Peripheral lymph nodes 25 / 30Toll-like receptors (TLRs) are part of which immune system?Adaptive Adaptive Passive Humoral Innate 26 / 30What is the function of the J chain in immunoglobulins? Joins monomers of IgA and IgM Inhibits antibody function Enhances Fc receptor binding Breaks down antigens 27 / 30Which immunoglobulin is primarily involved in mucosal immunity? IgG IgE IgM IgA 28 / 30Which interleukin is known as the "T cell growth factor"? IL-1 IL-2 IL-6 IL-10 29 / 30The complement system enhances immunity by: Increasing T cell count Opsonization and cell lysis Antigen production Cell apoptosis 30 / 30Which molecule is crucial for T-cell activation along with the TCR–MHC interaction? CD40 CD28 CD19 IgE Your score isThe average score is 30% 0% Restart quiz