Immunology Quiz: Test Your Knowledge Immunology QuizChallenge your understanding of immunology with our carefully curated quiz covering foundational to advanced concepts. This interactive set of multiple-choice questions (MCQs) includes topics like innate and adaptive immunity, antibodies, antigen presentation, hypersensitivity reactions, and immune disorders. Perfect for students, competitive exam aspirants, and microbiology enthusiasts looking to revise or reinforce their knowledge. Start learning smarter with instant feedback and explanations on LearnMicrobiology.com! NameEmail 1 / 30MHC class I molecules present antigens to: CD8+ T cells Macrophages CD4+ T cells B cells 2 / 30Which of the following diseases is an example of autoimmunity? Tuberculosis Rheumatoid arthritis HIV/AIDS Asthma 3 / 30Which of these cells produces antibodies? Plasma cells Macrophages T cells Dendritic cells 4 / 30Toll-like receptors (TLRs) are part of which immune system?Adaptive Passive Humoral Innate Adaptive 5 / 30Which of the following best describes antigenic drift? Minor mutations over time Inactivation of antigen Sudden, major changes in antigen Immune memory loss 6 / 30Which cell surface marker is found on all helper T cells? CD4 CD19 CD8 CD56 7 / 30The process of central tolerance occurs in the: Peripheral lymph nodes Liver Thymus and bone marrow Bloodstream 8 / 30Which antibody is most abundant in human serum? IgM IgE IgG IgA 9 / 30Which cytokine is primarily responsible for fever? IL-1 IL-10 IL-4 IFN-gamma 10 / 30Clonal selection refers to: Removal of self-reactive lymphocytes Natural killer cell activation Expansion of specific lymphocytes after antigen recognition Generation of T cell receptors 11 / 30Histamine release is most closely associated with which immune response? Autoimmunity Inflammation Allergy Antibody production 12 / 30Which immunoglobulin is primarily involved in mucosal immunity? IgA IgG IgE IgM 13 / 30Which of the following immunoglobulins can cross the placenta? IgG IgE IgA IgM 14 / 30Which molecule is crucial for T-cell activation along with the TCR–MHC interaction? CD28 CD19 IgE CD40 15 / 30Which pathway of complement activation requires antibodies? Lectin Lytic Classical Alternative 16 / 30Which of the following is NOT an antigen-presenting cell? B cell Macrophage Erythrocyte Dendritic cell 17 / 30What is the function of the J chain in immunoglobulins? Enhances Fc receptor binding Joins monomers of IgA and IgM Inhibits antibody function Breaks down antigens 18 / 30Which type of hypersensitivity is antibody-mediated cytotoxic? Type II Type IV Type III Type I 19 / 30Which is a feature of a secondary immune response? IgM predominance Faster and stronger antibody production Low antibody titers Slow onset 20 / 30Which interleukin is known as the "T cell growth factor"? IL-10 IL-1 IL-2 IL-6 21 / 30What is the primary function of the immune system? Digestion Oxygen transport Hormone production Defense against pathogens 22 / 30Phagocytosis is carried out primarily by: Mast cells Macrophages T-helper cells B cells 23 / 30Which is a function of Regulatory T cells (Tregs)? Suppress immune response Stimulate inflammation Present antigens Kill infected cells 24 / 30The term "opsonization" refers to: Antigen destruction by acid Coating of pathogens to enhance phagocytosis Lymphocyte apoptosis Antibody switching 25 / 30What type of immunity is acquired through vaccination? Artificial active immunity Passive immunity Innate immunity Natural immunity 26 / 30Which immunoglobulin appears first during a primary immune response? IgM IgG IgA IgE 27 / 30Which of the following is a component of the innate immune system? Antibodies Natural killer (NK) cells Memory B cells T cells 28 / 30Which transcription factor is activated by NF-κB in immune signaling? MyD88 p53 STAT6 NF-κB itself 29 / 30Which organ is responsible for the maturation of T lymphocytes? Thymus Spleen Liver Bone marrow 30 / 30The complement system enhances immunity by: Increasing T cell count Antigen production Opsonization and cell lysis Cell apoptosis Your score isThe average score is 65% 0% Restart quiz
