Immunology QuizChallenge your understanding of immunology with our carefully curated quiz covering foundational to advanced concepts. This interactive set of multiple-choice questions (MCQs) includes topics like innate and adaptive immunity, antibodies, antigen presentation, hypersensitivity reactions, and immune disorders. Perfect for students, competitive exam aspirants, and microbiology enthusiasts looking to revise or reinforce their knowledge. Start learning smarter with instant feedback and explanations on LearnMicrobiology.com! NameEmail 1 / 30Which of the following is NOT an antigen-presenting cell? Erythrocyte Dendritic cell Macrophage B cell 2 / 30Which transcription factor is activated by NF-κB in immune signaling? STAT6 NF-κB itself MyD88 p53 3 / 30Which of the following is a component of the innate immune system? T cells Natural killer (NK) cells Antibodies Memory B cells 4 / 30Which of these cells produces antibodies? Macrophages T cells Plasma cells Dendritic cells 5 / 30Which immunoglobulin is primarily involved in mucosal immunity? IgM IgE IgA IgG 6 / 30Which is a function of Regulatory T cells (Tregs)? Stimulate inflammation Present antigens Suppress immune response Kill infected cells 7 / 30Histamine release is most closely associated with which immune response? Allergy Inflammation Autoimmunity Antibody production 8 / 30Clonal selection refers to: Natural killer cell activation Generation of T cell receptors Removal of self-reactive lymphocytes Expansion of specific lymphocytes after antigen recognition 9 / 30Which interleukin is known as the "T cell growth factor"? IL-10 IL-1 IL-6 IL-2 10 / 30Which of the following immunoglobulins can cross the placenta? IgG IgM IgA IgE 11 / 30Phagocytosis is carried out primarily by: Mast cells B cells T-helper cells Macrophages 12 / 30The process of central tolerance occurs in the: Peripheral lymph nodes Thymus and bone marrow Bloodstream Liver 13 / 30Which pathway of complement activation requires antibodies? Alternative Lectin Lytic Classical 14 / 30Which is a feature of a secondary immune response? IgM predominance Faster and stronger antibody production Low antibody titers Slow onset 15 / 30Which type of hypersensitivity is antibody-mediated cytotoxic? Type III Type I Type II Type IV 16 / 30Which immunoglobulin appears first during a primary immune response? IgA IgG IgE IgM 17 / 30Which of the following best describes antigenic drift? Minor mutations over time Inactivation of antigen Sudden, major changes in antigen Immune memory loss 18 / 30MHC class I molecules present antigens to: B cells CD8+ T cells CD4+ T cells Macrophages 19 / 30Which antibody is most abundant in human serum? IgG IgM IgA IgE 20 / 30The term "opsonization" refers to: Lymphocyte apoptosis Antibody switching Antigen destruction by acid Coating of pathogens to enhance phagocytosis 21 / 30What is the primary function of the immune system? Oxygen transport Digestion Defense against pathogens Hormone production 22 / 30Which molecule is crucial for T-cell activation along with the TCR–MHC interaction? CD28 CD19 IgE CD40 23 / 30Which of the following diseases is an example of autoimmunity? Asthma Tuberculosis HIV/AIDS Rheumatoid arthritis 24 / 30What type of immunity is acquired through vaccination? Innate immunity Natural immunity Passive immunity Artificial active immunity 25 / 30Toll-like receptors (TLRs) are part of which immune system?Adaptive Innate Humoral Adaptive Passive 26 / 30What is the function of the J chain in immunoglobulins? Breaks down antigens Enhances Fc receptor binding Joins monomers of IgA and IgM Inhibits antibody function 27 / 30Which cytokine is primarily responsible for fever? IL-10 IFN-gamma IL-4 IL-1 28 / 30Which organ is responsible for the maturation of T lymphocytes? Bone marrow Thymus Liver Spleen 29 / 30The complement system enhances immunity by: Antigen production Increasing T cell count Cell apoptosis Opsonization and cell lysis 30 / 30Which cell surface marker is found on all helper T cells? CD19 CD4 CD8 CD56 Your score isThe average score is 30% 0% Restart quiz