Immunology Quiz: Test Your Knowledge Immunology QuizChallenge your understanding of immunology with our carefully curated quiz covering foundational to advanced concepts. This interactive set of multiple-choice questions (MCQs) includes topics like innate and adaptive immunity, antibodies, antigen presentation, hypersensitivity reactions, and immune disorders. Perfect for students, competitive exam aspirants, and microbiology enthusiasts looking to revise or reinforce their knowledge. Start learning smarter with instant feedback and explanations on LearnMicrobiology.com! NameEmail 1 / 30The term "opsonization" refers to: Coating of pathogens to enhance phagocytosis Lymphocyte apoptosis Antibody switching Antigen destruction by acid 2 / 30Which of the following best describes antigenic drift? Minor mutations over time Sudden, major changes in antigen Inactivation of antigen Immune memory loss 3 / 30Which pathway of complement activation requires antibodies? Classical Alternative Lytic Lectin 4 / 30The process of central tolerance occurs in the: Peripheral lymph nodes Thymus and bone marrow Bloodstream Liver 5 / 30Which immunoglobulin is primarily involved in mucosal immunity? IgM IgG IgA IgE 6 / 30Which of these cells produces antibodies? Dendritic cells Macrophages T cells Plasma cells 7 / 30What is the function of the J chain in immunoglobulins? Inhibits antibody function Breaks down antigens Enhances Fc receptor binding Joins monomers of IgA and IgM 8 / 30What is the primary function of the immune system? Defense against pathogens Digestion Oxygen transport Hormone production 9 / 30Which transcription factor is activated by NF-κB in immune signaling? NF-κB itself STAT6 MyD88 p53 10 / 30Which cytokine is primarily responsible for fever? IFN-gamma IL-1 IL-10 IL-4 11 / 30MHC class I molecules present antigens to: CD4+ T cells Macrophages CD8+ T cells B cells 12 / 30Which organ is responsible for the maturation of T lymphocytes? Spleen Liver Thymus Bone marrow 13 / 30Which of the following is NOT an antigen-presenting cell? B cell Macrophage Erythrocyte Dendritic cell 14 / 30What type of immunity is acquired through vaccination? Natural immunity Passive immunity Artificial active immunity Innate immunity 15 / 30Clonal selection refers to: Expansion of specific lymphocytes after antigen recognition Removal of self-reactive lymphocytes Natural killer cell activation Generation of T cell receptors 16 / 30Which molecule is crucial for T-cell activation along with the TCR–MHC interaction? CD28 CD40 IgE CD19 17 / 30Toll-like receptors (TLRs) are part of which immune system?Adaptive Adaptive Passive Innate Humoral 18 / 30Which is a function of Regulatory T cells (Tregs)? Present antigens Kill infected cells Stimulate inflammation Suppress immune response 19 / 30The complement system enhances immunity by: Antigen production Cell apoptosis Opsonization and cell lysis Increasing T cell count 20 / 30Which interleukin is known as the "T cell growth factor"? IL-10 IL-1 IL-2 IL-6 21 / 30Which is a feature of a secondary immune response? Faster and stronger antibody production Low antibody titers IgM predominance Slow onset 22 / 30Phagocytosis is carried out primarily by: Mast cells Macrophages B cells T-helper cells 23 / 30Which of the following immunoglobulins can cross the placenta? IgM IgE IgA IgG 24 / 30Which cell surface marker is found on all helper T cells? CD19 CD8 CD4 CD56 25 / 30Histamine release is most closely associated with which immune response? Autoimmunity Allergy Antibody production Inflammation 26 / 30Which antibody is most abundant in human serum? IgM IgG IgE IgA 27 / 30Which of the following diseases is an example of autoimmunity? Rheumatoid arthritis Tuberculosis HIV/AIDS Asthma 28 / 30Which of the following is a component of the innate immune system? Natural killer (NK) cells Memory B cells Antibodies T cells 29 / 30Which immunoglobulin appears first during a primary immune response? IgM IgE IgG IgA 30 / 30Which type of hypersensitivity is antibody-mediated cytotoxic? Type III Type IV Type I Type II Your score isThe average score is 52% 0% Restart quiz